Effect of Asmarihara kasaya curna (ASM)-an ayurvedic formulation on lipid profile after chronic administration

Abstract

Asmarihara Kasaya Curna (ASM), a classical Ayurvedic preparation which is widely used in Urolithiasis .The research was carried out in order to observe the effect of this formulation on lipid profile reveals that it possesses hypotriglyceridemic property after chronic administration for 45 consecutive days. In the male rats there was a statistically very highly significant decrease in the Triglycerides (p=0.001***) content in the plasma. On the contrary an increase in the Total Cholesterol (p=0.285NS), VLDL (p=0.173 NS) and LDL (p=0.023*) content in the plasma was noted. There was an insignificant decrease (p=0.771 NS) in HDL. In the female rats there was a statistically very highly significant decrease in the Triglycerides, content (p=0.001***) in the plasma. Interestingly none of the other changes in case of the total Cholesterol (p=0.924 NS), VLDL (p=0.329 NS), LDL (p=0.881 NS) and HDL (p=0.983 NS) were significantly different from their corresponding control values. But in male rats, the content of the LDL in plasma a statistically significant increase was noted which was different from female rats.